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KMID : 1144320160480040257
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감염과 화학요법
2016 Volume.48 No. 4 p.257 ~ p.266
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Indirect Effects of Pneumococcal Conjugate Vaccines in National Immunization Programs for Children on Adult Pneumococcal Disease
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Kim Young-Keun
LaFon David
Nahm Moon-H.
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Abstract
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The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have included PCVs in national immunization programs for children, the incidence of invasive pneumococcal disease caused by vaccine type Streptococcus pneumoniae has declined markedly, not only among the vaccinated pediatric population, but also among unvaccinated adults. In this review, we present a concise overview of the indirect effects of mass pediatric PCV immunization on unvaccinated adults.
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KEYWORD
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Pneumococcal vaccines, Pneumococcal infections, Mass vaccination, Immunity, Herd
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